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FOXM1 Human siRNA Oligo Duplex (Locus ID 2305)

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SKU
SR320176
FOXM1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • SR320176 is the updated version of SR301615.
  $518.00
In Stock*

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Other products for "FOXM1 or NM_001243088"

Specifications
Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
FOXM1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 2305)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_001243088, NM_001243089, NM_021953, NM_202002, NM_202003
UniProt ID Q08050
Synonyms FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT
Summary The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2011
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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Documents
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file-alt Citations

Persistent hypoxia promotes myofibroblast differentiation via GPR-81 and differential regulation of LDH isoenzymes in normal and idiopathic pulmonary fibrosis fibroblasts
Nho, Rice, Prasad et al
Physiol Rep (2023) 11 (17), e15759 DOI: 10.14814/phy2.15759
Cited by 20
AI Summary: OriGene products contributed to this study by providing siRNAs targeting FoxM1 (SR320176), LDHA (SR302665), and GPR-81 (SR3223850), which were used to silence these genes and investigate their roles in fibroblast differentiation under hypoxic conditions.
Snippet: … For silencing, control and IPF fibroblasts were transfected with 50 nM FoxM1, LDHA, or GPR-81 siRNA (catalog No. SR320176, SR302665, or SR3223850 from OriGene, respectively) using Lipofectamine 3000 (ThermoFisher, OH, #L3000001)
FigureFigureFigure
SPOCK1 overexpression induced by platelet-derived growth factor-BB promotes hepatic stellate cell activation and liver fibrosis through the integrin α5β1/PI3K/Akt signaling pathway
Du, Lin, Wang et al
Lab. Invest. (2020)
Cited by 48
AI Summary: OriGene’s puromycin was used to select hepatic stellate cells successfully transduced with lentivirus, enabling the study of SPOCK1’s role in liver fibrosis.
Snippet: The "LV-control" is an empty vector. The multiplicity of infection for lentivirus transfection is 100, in the presence of polybrene. Seventy-two hours after infection, puromycin (OriGene) was applied for 2 weeks for HSC cells selection;- The "LV-control" is an empty vector. The multiplicity of infection for lentivirus transfection is 100, in the presence of polybrene. Seventy-two hours after in...
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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