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CD44 Human siRNA Oligo Duplex (Locus ID 960)

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SKU
SR319622
CD44 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • SR319622 is the updated version of SR300683.
  $518.00
3 Weeks*

Frequently Bought Together (4)

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SR30002 Trilencer-27 Fluorescent-labeled transfection control siRNA duplex - 1 nmol
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "CD44 or NM_000610"

Specifications
Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
CD44 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 960)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_000610, NM_001001389, NM_001001390, NM_001001391, NM_001001392, NM_001202555, NM_001202556, NM_001202557
UniProt ID P16070
Synonyms CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1
Summary The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. provided by RefSeq, Jul 2008
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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Documents
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file-alt Citations

iTRAQ‑based proteomic analysis of the interaction of A549 human lung epithelial cells with Aspergillus fumigatus conidia
Zhang, He, Gao et al
Mol Med Rep (2020) 22 (6), 4601-4610 DOI: 10.3892/mmr.2020.11582
Cited by 5
AI Summary: In this study, OriGene products—specifically the NDRG1 shRNA (cat. no. TL312488) and CD44 shRNA (cat. no. TL320612)—were used to silence gene expression in A549 cells, enabling the researchers to investigate the roles of NDRG1 and CD44 in the cellular response to Aspergillus fumigatus infection.
FigureFigureFigure
iTRAQ‑based proteomic analysis of the interaction of A549 human lung epithelial cells with Aspergillus fumigatus conidia
Zhang, He, Gao et al
Mol Med Rep (2020) 22 (6), 4601-4610 DOI: 10.3892/mmr.2020.11582
Cited by 5
AI Summary: OriGene products, including siRNAs targeting CD44 (cat. no. SR319622) and NDRG1 (cat. no. SR307046) as well as a scrambled negative control siRNA (cat. no. SR30004), were used in this study to investigate the roles of specific genes in A549 lung epithelial cell responses to Aspergillus fumigatus infection.
Snippet: no. TT300001;OriGene Technologies, Inc.) (15). The siRNAs targeted to the CD44 (cat. no. SR319622) and NDRG1 (cat. no. SR307046) gene, and scrambled negative control siRNA (cat. no. SR30004) were purchased from OriGene Technologies, Inc
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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