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siRNA Related Product

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SKU
SR30004
Trilencer-27 Universal scrambled negative control siRNA duplex - 2 nmol
  $130.00
In Stock*

Frequently Bought Together (1)

TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00
Specifications
Specifications
Product Data
Quality Control This duplex was sequence verified and functionally validated.
Storage Store at -20°C.
Components
1 vial of universal scrambled negative control siRNA duplex (2 nmol)
Stability The control is stable for one year from date of shipping when stored at -20oC.
Shipping Ambient
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
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Documents
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file-alt Citations

lncRNA H19 downregulation mediates oxidative stress-induced osteogenic dysfunction
Shin, Park, Yoon et al
Bone (2027) 214, 118121 DOI: 10.1016/j.bone.2026.118121
Snippet: The following siRNAs used in the present study were purchased from Origene (Rockville, MD, USA): Padi2 siRNA (SR418983B and C), negative control siRNA (SR30004)
ILC2-derived IL-9 promotes eosinophil-mediated antitumor activity
Ko, Ham, Koh et al
Sci Immunol (2026) 11 (124), eadz0989 DOI: 10.1126/sciimmunol.adz0989
Snippet: Cells were transfected for 24 hours with either Atf3-specific siRNA (Origene, catalog no. SR404382), scrambled control siRNA (Origene, catalog no. SR30004), or Hprt-specific siRNA (positive control;Origene, catalog no. SR30003) using siTrans 2.0 transfection reagent (Origene, catalog no. TT320001). Knockdown efficiency was assessed by qPCR
Methylation-associated downregulation of CRABP1 marks an aggressive malignant epithelial cell state in thyroid carcinoma
Fu, Li, Huang et al
Front Cell Dev Biol (2026) 14, 1974822-1974822 DOI: 10.3389/fcell.2026.1974822
Snippet: mechanism.CRABP1 knockdown and overexpressionHTC-C3 cells were transfected at approximately 60%–70% confluence with a non-targeting control siRNA (siCon;OriGene, SR30004) or one of three independent human CRABP1-targeting siRNAs (OriGene, SR300971). SiRNAs were used at 10 nM with Lipofectamine RNAiMAX (Invitrogen, 13778075) according to the manufactur;- a non-targeting control siRNA (siCon;OriGene, SR30004) or one of three independent human CRABP1-targeting siRNAs (OriGene, SR300971). …
Loss of Syndecan-3 Drives a Pro-inflammatory, EndMT-prone Phenotype in Aortic Valve Endothelial Cells
Ezeokeke, Bedford, Stroschein et al
bioRxiv (2026)
AI Summary: OriGene’s Trilencer-27 Universal scrambled negative control siRNA duplex (cat. SR30004) was used as a non-targeting control in experiments assessing the effects of syndecan-3 silencing in aortic valve endothelial cells.
Snippet: A Trilencer-27 Universal scrambled negative control siRNA duplex (Origene, cat. SR30004) was used as the non-targeting control (NTC) at the same concentration. Twenty
A targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer
Torres-Fernández, Boehm, Kaufmann et al
Mol Cancer (2026) 25 (1) DOI: 10.1186/s12943-026-02750-2
AI Summary: OriGene contributed to this study by providing the control siRNA (siCTRL, OriGene #SR30004) used for transient knockdown experiments to investigate the role of nonsense-mediated decay in small cell lung cancer.
Snippet: siRNA transfection for transient knockdown: for transient siRNA transfection, Lipofectamine RNAiMAX reagent was used at a 10pmol RNA:2μL Lipofectamine ratio following the manufacturer’s instructions with the following siRNAs: siCTRL (Origene #SR30004)
FigureFigureFigure
Ferritinophagy Contributes to Iron Accumulation and Ferroptosis in Fuchs Endothelial Corneal Dystrophy
Shepard, Skeie, Shevalye et al
bioRxiv (2026)
AI Summary: OriGene products, specifically the three distinct 27-mer siRNA duplexes against human NCOA4 (Cat# SR305344) and the universal 27-mer scrambled siRNA duplex (Cat# SR30004), were used to selectively knock down NCOA4 expression in cell culture models to investigate the role of ferritinophagy in Fuchs Endothelial Corneal Dystrophy.
Snippet: A set of three distinct 27-mer siRNA duplexes against human NCOA4 (Cat#SR305344;referred to as siRNA-A, siRNA-B, and siRNA-C) as well as a universal 27-mer scrambled siRNA duplex (Cat#SR30004;referred to as (-)siRNA) were purchased from Origene Technologies (Rockville, MD, USA). Lipofectamine RNAiMax (Cat#13778150;ThermoFisher) was used as the transfection agent for the reverse transfection of HCEC-B4G12 and F35T cells with the anti
Showing 1-6 of 289 papers.
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