H2-Ke6 Mouse shRNA Plasmid (Locus ID 14979)
Specifications
| Product Data | |
| Locus ID | 14979 |
|---|---|
| Synonyms | D17H6S112E; H-2Ke6; Hsd17b8; Ke-6; Ke6; Ring2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | H2-Ke6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 14979). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC086927, NM_013543, NM_013543.1, NM_013543.2 |
| UniProt ID | P50171 |
| Summary | NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone (PubMed:9712896). The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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