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MAPKAP Kinase 2 (MAPKAPK2) Human shRNA Plasmid Kit (Locus ID 9261)

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SKU
TR320609
MAPKAPK2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Other products for "MAPKAP Kinase 2 or NM_004759"

Specifications
Specifications
Product Data
Locus ID 9261
Synonyms MAPKAP-K2; MK-2; MK2
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components MAPKAPK2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9261). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_004759, NM_032960, NM_032960.1, NM_032960.2, NM_032960.3, NM_004759.1, NM_004759.2, NM_004759.3, NM_004759.4, BC052584, BC036060, NM_032960.4, NM_004759.5
UniProt ID P49137
Summary This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis
Williams, Krug, McMillan et al
Mol. Biol. Cell (2016) 27 (15), 2341-50 DOI: 10.1091/mbc.E15-11-0773
AI Summary: OriGene’s retroviral shRNA constructs targeting human MK2 and a scrambled control were used to generate MK2-knockdown cell lines, enabling the study of MK2’s role in Dazl phosphorylation and spermatogenesis.
Snippet: B2;-glycerophosphate]).Generation of MK2-knockdown cell lineRetroviral shRNA constructs targeting human MK2 and a scrambled control shRNA construct were purchased from OriGene (Rockville, MD). Stably transfected SUM149 cells were selected with puromycin (1 μg/m
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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