MAPKAP Kinase 2 (MAPKAPK2) Rabbit Polyclonal Antibody

SKU TA351382

Rabbit Polyclonal Anti-MAPKAPK2 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 200-1000; WB positive control: Human chromaffin cells tumor tissue and A431 cells; IHC: 25-100; Positive control: Human liver cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MAPKAPK2
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 46 kDa
• Gene Name: mitogen-activated protein kinase-activated protein kinase 2
• Database Link:
  NP_116584
  P49137
• Background: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
• Synonyms: MAPKAP-K2; MK-2; MK2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: MAPK signaling pathway, Neurotrophin signaling pathway, VEGF signaling pathway