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TNFAIP3 Human shRNA Plasmid Kit (Locus ID 7128)

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SKU
TR320557
TNFAIP3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Other products for "TNFAIP3 or NM_001270507"

Specifications
Specifications
Product Data
Locus ID 7128
Synonyms A20; AISBL; OTUD7C; TNFA1P2
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components TNFAIP3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 7128). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001270507, NM_001270508, NM_006290, NM_006290.1, NM_006290.2, NM_006290.3, NM_001270507.1, NM_001270508.1, BC041790, BC064689, BC098379, BC113871, BC114480, NM_001270508.2, NM_001270507.2, NM_006290.4
UniProt ID P21580
Summary This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. provided by RefSeq, Jul 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Esophageal cancer cells convert the death signal from TRAIL into a stimulus for survival during acid/bile exposure
Chang, Dang, Che et al
Dig Liver Dis (2020) 52 (10), 1195-1200 DOI: 10.1016/j.dld.2020.04.013
Cited by 12
AI Summary: In this study, OriGene products—including TRADD (Cat# RC213682) and c-FLIP (Cat# RC211744) expression plasmids—were used to investigate how esophageal cancer cells resist TRAIL-induced cell death by overexpressing these proteins and altering apoptotic signaling pathways.
Showing 1-1 of 1 papers.
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