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IL17RC Human shRNA Plasmid Kit (Locus ID 84818)

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SKU
TR317649
IL17RC - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 84818
Synonyms CANDF9; IL17-RL; IL17RL
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components IL17RC - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 84818). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001203263, NM_001203264, NM_001203265, NM_032732, NM_153460, NM_153461, NM_153462, NM_153463, NR_037807, NM_153460.1, NM_153460.2, NM_153460.3, NM_153461.1, NM_153461.2, NM_153461.3, NM_032732.1, NM_032732.2, NM_032732.4, NM_032732.5, NM_001203265.1, NM_001203264.1, NM_001203263.1, NM_153463.1, BC006411, NM_001367278, NM_001367279, NM_001367280, NM_153461.4
UniProt ID Q8NAC3
Summary This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. provided by RefSeq, Feb 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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