IL17RC Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 25-100 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm, Cell membrane |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to N terminal 357 amino acids of Human Interleukin-17 receptor C |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | interleukin 17 receptor C |
| Database Link | |
| Background | This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA; which is predominantly expressed in hemopoietic cells; and binds with high affinity to only IL-17A; this protein is expressed in nonhemopoietic tissues; and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines; IL-17A and IL-17F; have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene; and it has been proposed that soluble; secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. |
| Synonyms | FLJ95963; FLJ96005; IL17-RL; IL17F receptor; IL17RL; interleukin 17 receptor-like; interleukin 17 receptor C; MGC10763 |
| Reference Data | |
| Protein Categories | Cytokines, Immune system diseases, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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