A1CF Human shRNA Plasmid Kit (Locus ID 29974)
Specifications
| Product Data | |
| Locus ID | 29974 |
|---|---|
| Synonyms | ACF; ACF64; ACF65; APOBEC1CF; ASP |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | A1CF - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 29974). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001198818, NM_001198819, NM_001198820, NM_014576, NM_138932, NM_138933, NM_014576.1, NM_014576.2, NM_014576.3, NM_138932.1, NM_138932.2, NM_138933.1, NM_138933.2, NM_001198819.1, NM_001198818.1, NM_001198820.1, BC130519, BC022263, BC054873, BC144194, BC144196, NM_001370130, NM_001370131, NM_014576.4 |
| UniProt ID | Q9NQ94 |
| Summary | Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. provided by RefSeq, Nov 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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