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ASCL1 Human shRNA Plasmid Kit (Locus ID 429)

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SKU
TR314633
ASCL1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Other products for "ASCL1 or NM_004316"

Specifications
Specifications
Product Data
Locus ID 429
Synonyms ASH1; bHLHa46; HASH1; MASH1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ASCL1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 429). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_004316, NM_004316.1, NM_004316.2, NM_004316.3, BC004425, BC004425.1, BC001638, BC002341, BC003134, BC031299, NM_004316.4
UniProt ID P50553
Summary This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1
Garcez, Diaz-Alonso, Crespo-Enriquez et al
Nat Commun (2015) 6, 6474 DOI: 10.1038/ncomms7474
Cited by 62
AI Summary: OriGene products contributed Cenpj shRNA, Ascl1 shRNA, and control shRNA plasmids, which were used to manipulate gene expression and investigate the roles of Cenpj and Ascl1 in cortical development in this study.
Snippet: Plasmids constructs and siRNAs. Cenpj shRNA (50 -TCCGACTGGATGCCTG GAAGAGAGCAGAA-30 ), Ascl1 shRNA (50 -AGAAGATGAGCAAGGTGGAGA CGCTGCGC-30 ) control shRNA (50 -GCACTACCAGAGCTAACTCAGATAGT ACT-30 ) plasmids were purchased from Origene. …
Showing 1-1 of 1 papers.
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