ASCL1 Rabbit Polyclonal Antibody

SKU
TA321640
Anti-ASCL1 Rabbit Polyclonal Antibody
  $305.00
In Stock*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-200
Positive control: Human ovarian cancer
Predicted cell location: Nucleus
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 215-228 amino acids of human achaete-scute complex homolog 1 (Drosophila)
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name achaete-scute family bHLH transcription factor 1
Database Link
Background This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Synonyms ASH1; bHLHa46; HASH1; MASH1
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system Diseases, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
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