DDX58 Human shRNA Plasmid Kit (Locus ID 23586)
Specifications
| Product Data | |
| Locus ID | 23586 |
|---|---|
| Synonyms | RIG-I; RIG1; RIGI; RLR-1; SGMRT2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | DDX58 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 23586). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_014314, NM_014314.1, NM_014314.2, NM_014314.3, BC070029, BC107731, BC132786, BC136610, NM_014314.4 |
| UniProt ID | O95786 |
| Summary | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. provided by RefSeq, Aug 2020 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Komune, Ichinohe, Ito et al
J. Virol (2011)
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