DDX58 Mouse Monoclonal Antibody [Clone ID: OTI6C1]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI6C1 |
|---|---|
| Application | ELISA (indirect), IF, IHC, WB |
| Recommended Dilution | WB 1:4000, IHC 1:150, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human DDX58(NP_055129) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 106.4 kDa |
| Gene Name | DExD/H-box helicase 58 |
| Database Link | |
| Background | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. provided by RefSeq, Jul 2008 |
| Synonyms | RIG-I; RIGI; RLR-1 |
| Reference Data | |
| Protein Categories | Cytokines, Intracellular Proteins |
| Protein Pathways | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI6C1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF506141 | Carrier-free (BSA/glycerol-free) DDX58 mouse monoclonal antibody, clone OTI6C1 (formerly 6C1) | 100 ug |
$620.00
|
|
| TA506141AM | DDX58 mouse monoclonal antibody,clone 6C1, Biotinylated | 100 ul |
$509.00
|
|
| TA506141BM | DDX58 mouse monoclonal antibody,clone 6C1, HRP conjugated | 100 ul |
$509.00
|
|
| TA506141S | DDX58 mouse monoclonal antibody, clone OTI6C1 (formerly 6C1) | 30 ul |
$200.00
|
|
Citations
Toscana virus non-structural protein NSs acts as E3 ubiquitin ligase promoting RIG-I degradation
Gori Savellini, Anichini, Gandolfo et al
PLoS Pathog. (2019) 15 (12), e1008186 DOI: 10.1371/journal.ppat.1008186
Gori Savellini, Anichini, Gandolfo et al
PLoS Pathog. (2019) 15 (12), e1008186 DOI: 10.1371/journal.ppat.1008186
Cited by 29
AI Summary: OriGene's anti-RIG-I (DDX58) polyclonal antibody was used in this study to detect and analyze RIG-I protein levels, supporting the investigation of how Toscana virus NSs promotes RIG-I degradation.
Snippet: m GmbH (Germany). The proteasome inhibitor MG-132 was purchased from Sigma-Aldrich (Milan, Italy). Mouse anti-6xHis tag antibody (GE Healthcare, Milan, Italy), anti-RIG-I (DDX58) polyclonal antibody (OriGene, Rockville, MD, USA), mouse anti-FLAG M2 monoclonal antibody (Agilent Technologies, Milan, Italy), mouse monoclonal anti-HA tag antibody, fluorescein (FITC)-labeled anti-mouse IgG and anti-mou
Showing 1-1 of 1 papers.
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