DHFR Human shRNA Plasmid Kit (Locus ID 1719)
Specifications
| Product Data | |
| Locus ID | 1719 |
|---|---|
| Synonyms | DHFRP1; DYR |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | DHFR - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1719). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000791, NM_001290354, NM_001290357, NR_110936, NM_000791.1, NM_000791.2, NM_000791.3, NM_001290357.1, NM_001290354.1, BC000192, BC003584, BC009634, BC070280, BC071996, NM_001290354.2, NM_001290357.2, NM_000791.4 |
| UniProt ID | P00374 |
| Summary | Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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