EVI1 (MECOM) Human shRNA Plasmid Kit (Locus ID 2122)
Specifications
| Product Data | |
| Locus ID | 2122 |
|---|---|
| Synonyms | AML1-EVI-1; EVI1; KMT8E; MDS1; MDS1-EVI1; PRDM3; RUSAT2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MECOM - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2122). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001105077, NM_001105078, NM_001163999, NM_001164000, NM_001205194, NM_004991, NM_005241, NM_005241.1, NM_005241.2, NM_001105078.1, NM_001105078.2, NM_001105078.3, NM_001105077.1, NM_001105077.2, NM_001105077.3, NM_001164000.1, NM_001163999.1, NM_004991.3, NM_001205194.1, BC069498, BC143952, BC130520, BC012450, BC031019, BC143951, NM_001366467, NM_001366469, NM_001366470, NM_001366471, NM_001366466, NM_001366468, NM_001366472, NM_001366473, NM_001366474, NM_001205194.2, NM_001164000.2, NM_001105078.4, NM_004991.4, NM_005241.4 |
| UniProt ID | Q13465 |
| Summary | The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. provided by RefSeq, Mar 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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