GADD45A Human shRNA Plasmid Kit (Locus ID 1647)
Specifications
| Product Data | |
| Locus ID | 1647 |
|---|---|
| Synonyms | DDIT1; GADD45 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | GADD45A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1647). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001199741, NM_001199742, NM_001924, NM_001924.1, NM_001924.2, NM_001924.3, NM_001199742.1, NM_001199741.1, BC011757, BC011757.2, NM_001199742.2, NM_001199741.2, NM_001924.4 |
| UniProt ID | P24522 |
| Summary | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.provided by RefSeq, Dec 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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