Glutaredoxin 1 (GLRX) Human shRNA Plasmid Kit (Locus ID 2745)

SKU
TR312745
GLRX - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 2745
Synonyms GRX; GRX1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components GLRX - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2745). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC010965, NM_001118890, NM_001243658, NM_001243659, NM_002064, NM_002064.1, NM_002064.2, NM_001118890.1, NM_001243658.1, NM_001243659.1, BC010965.1, BC005304, BC106075, NM_001118890.2, NM_001243658.2, NM_002064.3
UniProt ID P35754
Summary This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. provided by RefSeq, Aug 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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