Glutaredoxin 1 (GLRX) Human shRNA Plasmid Kit (Locus ID 2745)
Specifications
| Product Data | |
| Locus ID | 2745 |
|---|---|
| Synonyms | GRX; GRX1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | GLRX - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2745). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC010965, NM_001118890, NM_001243658, NM_001243659, NM_002064, NM_002064.1, NM_002064.2, NM_001118890.1, NM_001243658.1, NM_001243659.1, BC010965.1, BC005304, BC106075, NM_001118890.2, NM_001243658.2, NM_002064.3 |
| UniProt ID | P35754 |
| Summary | This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. provided by RefSeq, Aug 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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