KAT6B Human shRNA Plasmid Kit (Locus ID 23522)
Specifications
| Product Data | |
| Locus ID | 23522 |
|---|---|
| Synonyms | GTPTS; MORF; MOZ2; MYST4; qkf; querkopf; ZC2HC6B |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | KAT6B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 23522). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001256468, NM_001256469, NM_012330, NM_012330.1, NM_012330.2, NM_012330.3, NM_001256469.1, NM_001256468.1, BC014143, BC021128, BC048199, BC150270, BC150618, NM_001370133, NM_001370136, NM_001370140, NM_001370141, NM_001370143, NM_001370144, NM_001370132, NM_001370134, NM_001370135, NM_001370137, NM_001370138, NM_001370139, NM_001370142 |
| UniProt ID | Q8WYB5 |
| Summary | The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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