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NOXA1 Human shRNA Plasmid Kit (Locus ID 10811)

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SKU
TR311134
NOXA1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 10811
Synonyms NY-CO-31; p51NOX; SDCCAG31
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components NOXA1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 10811). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001256067, NM_001256068, NM_006647, NM_006647.1, NM_001256068.1, NM_001256067.1, BC041594, BC041594.1, BC110840, NM_006647.2, NM_001256067.2
UniProt ID Q86UR1
Summary This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC- and ABC-DLBCL cells in vitro and in vivo
Dasmahapatra, Lembersky, Son et al
Mol. Cancer Ther. (2012) 11 (5), 1122-32 DOI: 10.1158/1535-7163.MCT-12-0021
Cited by 6
AI Summary: OriGene's HuSH 29 mer short hairpin RNA (shRNA) construct against NOXA1 (catalog no. TF311134) was used in this study to knock down NOXA expression in SUDHL4 cells, enabling the authors to investigate the role of NOXA in the apoptotic response to combined carfilzomib and obatoclax treatment.
Snippet: HuSH 29 mer short hairpin RNA (shRNA) constructs against NOXA1 in a pRFP-C-RS vector from Origene Technologies, (catalog no TF311134) were used to knockdown NOXA in SUDHL4 cells through transient transfection.
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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