RFXANK Human shRNA Plasmid Kit (Locus ID 8625)
Specifications
| Product Data | |
| Locus ID | 8625 |
|---|---|
| Synonyms | ANKRA1; BLS; F14150_1; RFX-B |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | RFXANK - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8625). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001278727, NM_001278728, NM_003721, NM_134440, NM_003721.1, NM_003721.2, NM_003721.3, NM_134440.1, NM_134440.2, NM_001278727.1, BC114563, BC114558, BM682278, BM712354, NM_001370233, NM_001370235, NM_001370237, NM_001370238, NM_001370234, NM_001370236, NM_003721.4 |
| UniProt ID | O14593 |
| Summary | Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jul 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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