SDHB Human shRNA Plasmid Kit (Locus ID 6390)
Specifications
| Product Data | |
| Locus ID | 6390 |
|---|---|
| Synonyms | CWS2; IP; MC2DN4; PGL4; SDH; SDH1; SDH2; SDHIP |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SDHB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 6390). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_003000, NM_003000.1, NM_003000.2, BC007840, NM_003000.3 |
| UniProt ID | P21912 |
| Summary | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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