SDHB Mouse Monoclonal Antibody [Clone ID: OTI3F5]
Specifications
| Product Data | |
| Clone Name | OTI3F5 |
|---|---|
| Application | IHC, Simple Western, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 ; Simple Western 1:20-1:50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human SDHB(NP_002991) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 28.8 kDa |
| Gene Name | succinate dehydrogenase complex iron sulfur subunit B |
| Database Link | |
| Background | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. provided by RefSeq, Jul 2008 |
| Synonyms | CWS2; IP; MC2DN4; PGL4; SDH; SDH1; SDH2; SDHIP |
| Reference Data | |
| Protein Categories | Cancer: Endocrine, Cancer: Gastrointestinal, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Citrate cycle (TCA cycle), Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3F5" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF808102 | Carrier-free (BSA/glycerol-free) SDHB mouse monoclonal antibody, clone OTI3F5 (formerly 3F5) | 100 ug |
$620.00
|
|
| TA808102AM | SDHB mouse monoclonal antibody, clone OTI3F5 (formerly 3F5), Biotinylated | 100 ul |
$509.00
|
|
| TA808102BM | SDHB mouse monoclonal antibody, clone OTI3F5 (formerly 3F5), HRP conjugated | 100 ul |
$509.00
|
|
| TA808102S | SDHB mouse monoclonal antibody, clone OTI3F5 (formerly 3F5) | 30 ul |
$200.00
|
|
Citations
Hou, Zhang, Jian et al
Cell Res. (2019) 29 (9), 754-766 DOI: 10.1038/s41422-019-0208-x
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