SPOP Human shRNA Plasmid Kit (Locus ID 8405)
Specifications
| Product Data | |
| Locus ID | 8405 |
|---|---|
| Synonyms | BTBD32; NEDMACE; NEDMIDF; NSDVS1; NSDVS2; TEF2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SPOP - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8405). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001007226, NM_001007227, NM_001007228, NM_001007229, NM_001007230, NM_003563, NM_001007229.1, NM_001007228.1, NM_001007226.1, NM_001007227.1, NM_003563.1, NM_003563.2, NM_003563.3, NM_001007230.1, BC001269, BC001269.1, BC003385, BC003385.1, BM693397, NM_001370730, NM_001370731, NM_001370732, NM_001007228.2 |
| UniProt ID | O43791 |
| Summary | This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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