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USP19 Human shRNA Plasmid Kit (Locus ID 10869)

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SKU
TR308463
USP19 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 10869
Synonyms ZMYND9
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components USP19 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 10869). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001199160, NM_001199161, NM_001199162, NM_006677, NM_001351098, NM_001351099, NM_001351100, NM_001351101, NM_001351102, NM_001351103, NM_001351104, NM_001351105, NM_001351106, NM_001351107, NM_001351108, NM_006677.1, NM_006677.2, NM_001199162.1, NM_001199161.1, NM_001199160.1, BC014934, BC048269, BC065909, BC082241, BC106029, BC128088, BC142660, BC142727, BC146752
UniProt ID O94966
Summary Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

USP19 Enhances MMP2/MMP9-Mediated Tumorigenesis in Gastric Cancer
Dong, Guo, Wang et al
Onco Targets Ther (2020) 13, 8495-8510 DOI: 10.2147/OTT.S240543
AI Summary: OriGene products contributed to this study by providing the USP19 overexpression plasmid (RC214190, Myc-DDK-tagged Human USP19, NM_006677, transcript variant 4) and the vector control (pCMV6-Entry, CAT#: PS100001), which were used to manipulate USP19 expression in gastric cancer cell lines for functional analyses.
Snippet: The specific kit for knockdown of USP19 was ordered from the commercial company (OriGene, Ltd.;USP19 Human shRNA Plasmid Kit [Locus ID 10,869], CAT#: TR308463, ordered from https://www. … com/catalog/rnai/shrna-plasmids/tr308463/usp19-humanshrna- plasmid-kit- locus- id-10,869). These shRNA constructs were designed against multiple splice variants at this gene locus, as well as the negative control-empty vector (pRS, CAT#: TR20003)
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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