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USP17L2 Human shRNA Plasmid Kit (Locus ID 377630)

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SKU
TR307933
USP17L2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 377630
Synonyms DUB-3; DUB3; USP17
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components USP17L2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 377630). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_201402, NM_201402.1, NM_201402.2, BC156290, BC157073
UniProt ID Q6R6M4
Summary DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for background information.supplied by OMIM, Mar 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression
McFarlane, Kelvin, de la Vega et al
Cancer Res (2010) 70 (8), 3329-39 DOI: 10.1158/0008-5472.CAN-09-4152
AI Summary: In this study, OriGene’s USP17 shRNA (OriGene: TF314881) was used to deplete USP17 expression in cells, enabling the authors to demonstrate that USP17 is essential for G1-S cell cycle progression and tumor cell proliferation.
Showing 1-1 of 1 papers.
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