ABCB4 Human shRNA Plasmid Kit (Locus ID 5244)
Specifications
| Product Data | |
| Locus ID | 5244 |
|---|---|
| Synonyms | ABC21; GBD1; ICP3; MDR2; MDR2/3; MDR3; PFIC-3; PGY3 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | ABCB4 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5244). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000443, NM_018849, NM_018850, NM_018849.1, NM_018849.2, NM_018850.2, NM_000443.1, NM_000443.2, NM_000443.3, BC042531, BC042531.1, BC020618, NM_018849.3 |
| UniProt ID | P21439 |
| Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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