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NANOG Human shRNA Plasmid Kit (Locus ID 79923)

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SKU
TR303039
NANOG - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Other products for "NANOG or NM_001297698"

Specifications
Specifications
Product Data
Locus ID 79923
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components NANOG - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 79923). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001297698, NM_024865, NM_024865.1, NM_024865.2, NM_024865.3, NM_001297698.1, BC069807, BC098275, BC099704, BC160187, NM_001297698.2, NM_024865.4
UniProt ID Q9H9S0
Summary The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Sep 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

CD133(+) cancer stem cells promoted by VEGF accelerate the recurrence of hepatocellular carcinoma
Liu, Hao, Ouyang et al
Sci Rep (2017) 7, 41499 DOI: 10.1038/srep41499
AI Summary: OriGene products contributed to this study by providing lentiviral shRNA constructs targeting Nanog and VEGFR2, which were used to investigate the roles of these genes in cancer stem cell function and hepatocellular carcinoma recurrence.
Snippet: described 16 . Briefly, cells were transfected with lentiviral constructs expressing shRNAs for Nanog, VEGFR2 (OriGene, MD, USA) or sh Ctrl for 24 hours. Positive cells were selected with puromycin for 7 days. Recombinant ... All 5 versions Cite SaveSaving
FigureFigureFigure
Overexpression of NANOG in gestational trophoblastic diseases: effect on apoptosis, cell invasion, and clinical outcome
Siu, Wong, Chan et al
Am J Pathol (2008) 173 (4), 1165-72 DOI: 10.2353/ajpath.2008.080288
Cited by 80
AI Summary: OriGene products contributed to this study by providing the NANOG shRNA used for stable knockdown experiments in JEG-3 choriocarcinoma cells, enabling the authors to assess NANOG’s role in apoptosis, cell invasion, and disease progression.
FigureFigureFigure
Showing 1-2 of 2 papers.
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