NODAL Human shRNA Plasmid Kit (Locus ID 4838)
Specifications
| Product Data | |
| Locus ID | 4838 |
|---|---|
| Synonyms | HTX5 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | NODAL - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4838). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001329906, NM_018055, NM_018055.2, NM_018055.3, NM_018055.4, BC112025, BC112025.1, BC033585, BC039861, BC104976 |
| UniProt ID | Q96S42 |
| Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. provided by RefSeq, Aug 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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