PDE11A Human shRNA Plasmid Kit (Locus ID 50940)
Specifications
| Product Data | |
| Locus ID | 50940 |
|---|---|
| Synonyms | PPNAD2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PDE11A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 50940). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001077196, NM_001077197, NM_001077358, NM_016953, NM_001077358.1, NM_016953.1, NM_016953.2, NM_016953.3, NM_001077196.1, NM_001077197.1, BC114431, BC112393, NM_001077358.2, NM_001077197.2, NM_001077196.2, NM_016953.4 |
| UniProt ID | Q9HCR9 |
| Summary | The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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