PDE11A Rabbit Polyclonal Antibody

SKU
TA379725
PDE11A Rabbit polyclonal Antibody
  $410.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application ELISA, ICC/IF, WB
Recommended Dilution WB,1:500 - 1:2000
IF/ICC,1:50 - 1:200
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Mouse, Rat
Modification Unmodified
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Buffer Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 105kDa
Gene Name phosphodiesterase 11A
Database Link
Background The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms FLJ23693; MGC133355; MGC133356; OTTHUMP00000205272; PDE11A1; PDE11A2; PDE11A3; PPNAD2
Reference Data
Protein Categories Cytokines, Endocrine and metabolic diseases, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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