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PYHIN1 Human shRNA Plasmid Kit (Locus ID 149628)

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SKU
TR302175
PYHIN1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 149628
Synonyms IFIX
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PYHIN1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 149628). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_152501, NM_198928, NM_198929, NM_198930, NM_198929.1, NM_198929.2, NM_198929.3, NM_198929.4, NM_198928.1, NM_198928.2, NM_198928.3, NM_198928.4, NM_198930.1, NM_198930.2, NM_198930.3, NM_152501.1, NM_152501.2, NM_152501.3, NM_152501.4, BC090944, BC090944.1, BC020822, BC073133, BC114470, BC139741, NM_198930.4, NM_198928.5, NM_152501.5, NM_198929.5
UniProt ID Q6K0P9
Summary The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Aug 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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