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Positive shRNA control against Luciferase (pRS Vector)

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SKU
TR30002
HuSH 29-mer shRNA against Luciferase Protein (in pRS Vector), 5 ug
  $270.00
In Stock*
Specifications
Specifications
Product Data
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store the vector DNA at -20°C.
Stability Vector DNA is stable for at least one year from date of receipt when stored at -20°C.
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file-alt Citations

PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer
Chen, Sheng, Ma et al
Mol Med Rep (2021) 24 (5) DOI: 10.3892/mmr.2021.12440
Cited by 19
AI Summary: OriGene products, specifically PLAC1 shRNA1, PLAC1 shRNA2, and PLAC1 cDNA lentiviral constructs, were used in this study to manipulate PLAC1 expression in cervical cancer cells, enabling the authors to investigate PLAC1's role in cell proliferation, invasion, and survival prognosis.
Snippet: RNA silencing and cDNA overexpression. Lentivirus harboring two short hairpin RNAs (shRNAs) targeting PLAC1 gene (PLAC1 shRNA1 and PLAC1 shRNA2) or PLAC1 cDNA were designed and produced by OriGene Technologies, Inc
FigureFigureFigure
Epigenetic events involved in OCT1-dependent impaired response of hepatocellular carcinoma to sorafenib
Al-Abdulla, Lozano, Macias et al
Br. J. Pharmacol. (2018)
AI Summary: OriGene products contributed to this study by providing commercial DNA oligonucleotides for shRNA targeting hOCT1 (sh-hOCT1), which were used as positive controls to investigate the role of hOCT1 in hepatocellular carcinoma response to sorafenib.
Snippet: Commercial DNA oligonucleotides for shRNA targeting hOCT1 (sh-hOCT1;positive control) were obtained from Origene. A shRNA targeted against firefly luciferase (Luc2) was used as a negative control (Gonzalez-Sanchez et al., 2016). Four oligonucleotides per miRNA
ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction
He, Ma, Tian et al
PLoS Pathog. (2017) 13 (6), e1006347 DOI: 10.1371/journal.ppat.1006347
AI Summary: OriGene’s HuSH 29mer shRNA constructs against ERRα were used in this study to specifically knock down ERRα expression and investigate its role in regulating antiviral innate immunity.
Snippet: HuSH 29mer shRNA constructs against ERRα kit was purchased from OriGene Company
An integrated transcriptomics-guided genome-wide promoter analysis and next-generation proteomics approach to mine factor(s) regulating cellular differentiation
Mandal, Bader, Kumar et al
DNA Res. (2017)
AI Summary: OriGene contributed to this study by providing specific shRNA used for the knockdown of the YY1 transcription factor in Sertoli cells, enabling the authors to investigate YY1's role in cellular differentiation and spermatogenesis.
Snippet: ...specific shRNA were obtained from OriGene (USA). The forward and...Louis, USA). The primary antibodies used were anti-YY1 alpha...No.4967L). Secondary antibodies used were anti-rabbit-horseradish...BSA for 30min. Primary antibody (Abcam, Cat. no. ab12132...
Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche
Reticker-Flynn, Bhatia
Cancer Discov (2014)
AI Summary: In this study, OriGene’s C2GnT2 and St6GalNAcIV expression plasmids were used to manipulate glycosyltransferase activity in cancer cells, enabling the authors to demonstrate how altered glycosylation promotes lung cancer metastasis via enhanced adhesion to galectin-3 in the metastatic niche.
Snippet: Page 1. 1 Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche Nathan E. ReticNerYFlynn1,2 and Sangeeta N. Bhatia1,2,3,4,5k 1. David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute ... Cite SaveSaving
Regulation of the human papillomavirus type 18 E6/E6AP ubiquitin ligase complex by the HECT domain-containing protein EDD
Tomaic, Pim, Thomas et al
J. Virol. (2011) 85 (7), 3120-7 DOI: 10.1128/JVI.02004-10
Cited by 8
AI Summary: OriGene’s nonspecific shRNA and shRNA against EDD were used to manipulate EDD expression levels in cells, enabling the study of EDD's regulatory role in the HPV-18 E6/E6AP ubiquitin ligase complex.
Snippet: cells were transfected using Lipofectamine 2000 (Invitrogen) with nonspecific short hairpin RNA (shRNA;OriGene) as a control and shRNA against EDD (OriGene). ... EDD in the absence of E6AP, we analyzed the ability of a purified GST-E6 fusion protein to pull down EDD from
Showing 1-6 of 7 papers.
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