Cdk5 Rat shRNA Plasmid (Locus ID 140908)

SKU
TL712474
Cdk5 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 140908
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Cdk5 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 140908). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_080885, NM_080885.1
UniProt ID Q03114
Summary serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression RGD, Feb 2006
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

p39-associated Cdk5 activity regulates dendritic morphogenesis
Ouyang, Chen, Wang et al
Sci Rep (2020) 10 (1), 18746 DOI: 10.1038/s41598-020-75264-6
Cited by 18
AI Summary: OriGene’s mouse Wdfy1 CDS plasmid (MR214818) was used to generate expression constructs for WDFY1 overexpression in rat cortical neurons, enabling the study of WDFY1's role downstream of Cdk5/p39 in dendritic morphogenesis.
Snippet: … The expression construct of Wdfy1 was subcloned from the mouse Wdfy1 CDS plasmid (MR214818, Origene) to the pcDNA3 vector. The overexpression efficiency of WDFY1 in rat cortical neurons was also confirmed (Supplementary Fig. … The expression constructs of Cdk5, dominant-negative, kin;Te expression construct of Wdfy1 was subcloned from the mouse Wdfy1 CDS plasmid (MR214818, Origene) to the pcDNA3 vector. Te overexpression efciency of WDFY1 in rat cortical neurons was also confrmed (Supplementary Fig. S2k,S2l)
Showing 1-1 of 1 papers.
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