Nr4a1 Rat shRNA Plasmid (Locus ID 79240)

SKU
TL711049
Nr4a1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 79240
Synonyms HMR; Ngfi-b; Nur77
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Nr4a1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 79240). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_024388, NM_024388.1, NM_024388.2, BC097313
UniProt ID P22829
Summary putative ligand-dependent transcriptional activator RGD, Feb 2006
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion
Reynolds, Hancock, Ray et al
Am. J. Physiol. Endocrinol. Metab. (2016)
Cited by 51
AI Summary: OriGene’s pGFP-C-shLenti plasmid and Lentiviral Packaging Plasmids were used to generate lentivirus for shRNA-mediated knockdown of Nr4a1 and Nr4a3, enabling the study of their roles in β-cell mitochondrial function and insulin secretion.
Snippet: shRNA cassette (termed shCTRL) were cloned into the pGFP-C-shLenti plasmid 131 (OriGene). Lentivirus was produced by transfecting HEK 293T cells with the respective 132 pGFP-C-shLenti plasmid and packaging plasmids using the Origene Lentiviral 133 ... Cite SaveSaving
Bile Acids Regulate Nuclear Receptor (Nur77) Expression and Intracellular Location to Control Proliferation and Apoptosis
Hu, Chau, Liu et al
Mol. Cancer Res. (2014)
AI Summary: OriGene products contributed to this study by providing shRNA constructs in a lentiviral GFP vector against Nur77 and the MegaTran 1.0 transfection reagent, which were used to knock down Nur77 expression and facilitate gene delivery in cancer cell experiments.
Snippet: shRNA constructs in lentiviral GFP vector against Nur77 were obtained from OriGene Technologies (Rockville, MD). For transient transfection, R-HCT116 and R-Huh7 cells were transfected with shRNA plasmids (1μg/1×105 Cells) using MegaTran 1.0 reagent (OriGene ... Cite SaveSaving
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