Sdc1 Rat shRNA Plasmid (Locus ID 25216)
SKU
TL709630
Sdc1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 25216 |
|---|---|
| Synonyms | HSPG; Synd1; SYNDECA; Syndecan |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Sdc1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 25216). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_013026, NM_013026.1, NM_013026.2, BC061834 |
| UniProt ID | P26260 |
| Summary | mouse homolog promotes cell-cell adhesion RGD, Feb 2006 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Omega-3 fatty acids induce apoptosis in human breast cancer cells and mouse mammary tissue through syndecan-1 inhibition of the MEK-Erk pathway
Sun, Hu, Gu et al
Carcinogenesis (2011) 32 (10), 1518-24 DOI: 10.1093/carcin/bgr132
Sun, Hu, Gu et al
Carcinogenesis (2011) 32 (10), 1518-24 DOI: 10.1093/carcin/bgr132
Cited by 77
AI Summary: OriGene’s SDC-1 plasmid was used as the template to amplify syndecan-1 cDNA, enabling the study of SDC-1’s role in omega-3 fatty acid-induced apoptosis in breast cancer cells.
Snippet: The SDC-1 ectodomain complementary DNA (cDNA) was amplified by polymerase chain reaction using the SDC-1 plasmid (OriGene Technologies, Rockville, MD) as the source of template, 5′-gcagaattcggcagcatgaggcgcgcggcgctct-3′ as the forward primer and 5
Syndecan-1-dependent suppression of PDK1/Akt/bad signaling by docosahexaenoic acid induces apoptosis in prostate cancer
Hu, Sun, Owens et al
Neoplasia (2010) 12 (10), 826-36 DOI: 10.1593/neo.10586
Hu, Sun, Owens et al
Neoplasia (2010) 12 (10), 826-36 DOI: 10.1593/neo.10586
Cited by 75
AI Summary: OriGene products contributed to this study by providing SDC-1 small interfering RNA (siRNA) for gene silencing experiments, enabling the authors to demonstrate the role of SDC-1 in DHA-induced apoptosis in prostate cancer cells.
Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells
Sun, Berquin, Owens et al
Cancer Res (2008) 68 (8), 2912-9 DOI: 10.1158/0008-5472.CAN-07-2305
Sun, Berquin, Owens et al
Cancer Res (2008) 68 (8), 2912-9 DOI: 10.1158/0008-5472.CAN-07-2305
AI Summary: In this study, OriGene’s SDC-1 small interfering RNA (siRNA) was used to silence syndecan-1 expression in human breast cancer cells, demonstrating that up-regulation of syndecan-1 is essential for n-3 PUFA-induced apoptosis.
Showing 1-3 of 3 papers.
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