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Foxa1 Rat shRNA Plasmid (Locus ID 25098)

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SKU
TL709363
Foxa1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 25098
Synonyms Hnf3a
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Foxa1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 25098). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_012742, NM_012742.1
UniProt ID P23512
Summary may act as a transcription factor for hepatocyte specific gene expression RGD, Feb 2006
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation
DeGraff, Clark, Cates et al
PLoS ONE (2012) 7 (5), e36669 DOI: 10.1371/journal.pone.0036669
Cited by 111
AI Summary: OriGene contributed shRNA constructs (FOXA1 targeted shRNA and scrambled shRNA control) used to generate RT4 bladder cancer cell lines with reduced FOXA1 expression, enabling the study of FOXA1’s role in tumor proliferation and differentiation.
Snippet: RT4 cells were puromycin selected to stably express a FOXA1 targeted shRNA construct resulting in decreased FOXA1 expression (RT4-FOXA1 KD) or scrambled shRNA expressing control cells (RT4-Scr) according to manufactures instructions (Origene, Rockville, MD).
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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