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Bdnf Rat shRNA Plasmid (Locus ID 24225)

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SKU
TL709161
Bdnf - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 24225
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Bdnf - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 24225). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001270630, NM_001270631, NM_001270632, NM_001270633, NM_001270634, NM_001270635, NM_001270636, NM_001270637, NM_001270638, NM_012513, NM_012513.1, NM_012513.2, NM_012513.3, NM_012513.4, NM_001270631.1, NM_001270632.1, NM_001270633.1, NM_001270634.1, NM_001270635.1, NM_001270636.1, NM_001270637.1, NM_001270638.1, NM_001270630.1, BC087634
UniProt ID P23363
Summary plays a role in the development of hippocampal long term potentiation; involved in regulation of synaptic plasticity RGD, Feb 2006
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Local presynaptic activity gates homeostatic changes in presynaptic function driven by dendritic BDNF synthesis
Jakawich, Nasser, Strong et al
Neuron (2010) 68 (6), 1143-58 DOI: 10.1016/j.neuron.2010.11.034
Cited by 179
AI Summary: In this study, OriGene’s Bdnf shRNA (TL502166) was used to specifically knock down BDNF expression, enabling the authors to demonstrate that postsynaptic, dendritically synthesized BDNF is required for retrograde homeostatic modulation of presynaptic function.
FigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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