Rora Rat shRNA Plasmid (Locus ID 300807)

SKU
TL705407
Rora - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 300807
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Rora - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 300807). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001106834, NM_001106834.1
Summary The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. provided by RefSeq, Feb 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Sertoli cell specific knockdown of RAR-related orphan receptor (ROR) alpha at puberty reduces sperm count in rats
Mandal, Sarkar, Sharma et al
Gene (2017)
AI Summary: In this study, the hairpin and seed sequences for ROR-alpha specific shRNA, obtained from OriGene (USA), were used to design plasmid constructs for Sertoli cell-specific knockdown of ROR-alpha in rats, enabling investigation of its role in spermatogenesis.
Snippet: min each). 2.4. Plasmid constructs design. The hairpin (TCAAGAG) and seed (CAGTTGTGTGCTATCAAGATTACAGAAGC) sequence of ROR alpha specific shRNA were obtained from the web database of OriGene, USA. The ...;... min each). 2.4. Plasmid constructs design. The hairpin (TCAAGAG) and seed (CAGTTGTGTGCTATCAAGATTACAGAAGC) sequence of ROR alpha specific shRNA were obtained from the web database of OriGene, U...
Showing 1-1 of 1 papers.
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