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Rec8 Rat shRNA Plasmid (Locus ID 290227)

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SKU
TL701430
Rec8 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "Rec8 or NM_001011916"

Specifications
Specifications
Product Data
Locus ID 290227
Synonyms Rec8L1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Rec8 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 290227). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001011916, BC079023
UniProt ID Q6AYJ4
Summary Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

REC8 inhibits EMT by downregulating EGR1 in gastric cancer cells
Zhao, Geng, Duan et al
Oncol. Rep. (2018)
AI Summary: OriGene contributed to this study by providing the REC8 shRNA (cat. no. TG309883), which was used to knock down REC8 expression and investigate its role in inhibiting EMT in gastric cancer cells.
Snippet: atmosphere of 5% CO2. REC8 shRNA, REC8 and EGR1 overexpression constructs and infection. REC8 shRNA was purchased from Origene Technologies, Inc. (cat. no. TG309883;Rockville, MD, USA). For the overexpression
REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype
Yu, Liang, Wang et al
Oncogene (2016)
Cited by 60
AI Summary: OriGene contributed to this study by providing shRNA vectors targeting REC8, which were used to knock down REC8 expression in gastric epithelial cells to investigate its tumor suppressor function.
Snippet: Knockdown of REC8. A set of vectors carrying shRNAs against REC8 was purchased from Origene (Rockville, MD, USA). The REC8-expressing cell lines GES-1 and AGS were transfected with vectors carrying scrambled sequence (sh-scrambled) as negative control ... Cite SaveSaving
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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