Cactin Mouse shRNA Plasmid (Locus ID 70312)
SKU
TL519394
Cactin - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 70312 |
|---|---|
| Synonyms | 2510012J08Rik |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Cactin - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 70312). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_027381, NM_027381.1, NM_027381.2, BC151180, BC023696, BC150986 |
| UniProt ID | Q9CS00 |
| Summary | Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
APOE ε2 is associated with increased tau pathology in primary tauopathy
Zhao, Liu, Van Ingelgom et al
Nat Commun (2018) 9 (1), 4388 DOI: 10.1038/s41467-018-06783-0
Zhao, Liu, Van Ingelgom et al
Nat Commun (2018) 9 (1), 4388 DOI: 10.1038/s41467-018-06783-0
AI Summary: OriGene’s mouse actin plasmid DNA was used as a quantitative standard in real-time PCR assays to measure gene expression levels in this study investigating APOE ε2’s association with increased tau pathology.
Snippet: Article.;;... es were run on a CFX96 Real-Time PCR Detection System (Bio-Rad, Hercules, CA). The absolute amount of each gene was obtained by referring to a standard curve consisting of mouse actin plasmid DNA (Origene, Rockville, MD) or human TauP301L plasmid DNA at 10 pg, 5 pg, 1 pg, 100 fg, and 10 fg. All samples and standard plasmid DNA were run in duplicate. RNA isolation and real-time PCR ...
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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