Dpy30 Mouse shRNA Plasmid (Locus ID 66310)
Specifications
| Product Data | |
| Locus ID | 66310 |
|---|---|
| Synonyms | 2810410M20Rik; C87842 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Dpy30 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 66310). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC002240, NM_001146222, NM_001146223, NM_001146224, NM_024428, NM_001146224.1, NM_001146222.1, NM_001146223.1, NM_024428.1, NM_024428.2, NM_024428.3, NM_024428.4 |
| UniProt ID | Q99LT0 |
| Summary | As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and histone H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. May also play an indirect or direct role in endosomal transport.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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