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Svbp Mouse shRNA Plasmid (Locus ID 69216)

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SKU
TL517601
Svbp - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 69216
Synonyms 2410005K17Rik; AI851162; Ccdc23
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Svbp - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 69216). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC002274, NM_001038998, NM_024462, NM_024462.1, NM_024462.2, NM_001038998.1, NM_001038998.2
UniProt ID Q99LQ4
Summary Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin (PubMed:29146868). Also required to enhance the solubility and secretion of VASH1 and VASH2 (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation
Aillaud, Bosc, Peris et al
Science (2017) 358 (6369), 1448-1453 DOI: 10.1126/science.aao4165
Cited by 298
AI Summary: In this study, OriGene products including shRNA constructs (OriGene, TL313954, TL320817) were used to knock down vasohibin-1 and vasohibin-2 expression, enabling the researchers to investigate the roles of these proteins in tubulin detyrosination and neuron differentiation.
Showing 1-1 of 1 papers.
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