Dnajb6 Mouse shRNA Plasmid (Locus ID 23950)
Specifications
| Product Data | |
| Locus ID | 23950 |
|---|---|
| Synonyms | HSJ-2; mDj4; Mrj |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Dnajb6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 23950). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC003702, BC083349, NM_001037940, NM_001037941, NM_001127367, NM_011847, NM_001359198, NR_152863, NM_001127367.1, NM_001037940.1, NM_001037940.2, NM_001037940.3, NM_001037940.4, NM_011847.1, NM_011847.2, NM_011847.3, NM_011847.4, NM_001037941.1, NM_001037941.2, NM_001037941.3 |
| UniProt ID | O54946 |
| Summary | Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (By similarity). Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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