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Scg3 Mouse shRNA Plasmid (Locus ID 20255)

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SKU
TL516044
Scg3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 20255
Synonyms 1B1075; AI385542; Chgd; SgIII
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Scg3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 20255). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC024785, NM_001164790, NM_009130, NM_001164790.1, NM_009130.1, NM_009130.2, NM_009130.3
UniProt ID P47867
Summary Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed:16219686). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (PubMed:12388744). May also play a role in angiogenesis (PubMed:28330905). Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Carboxypeptidase E and Secretogranin III Coordinately Facilitate Efficient Sorting of Proopiomelanocortin to the Regulated Secretory Pathway in AtT20 Cells
Cawley, Rathod, Young et al
Mol. Endocrinol. (2016) 30 (1), 37-47 DOI: 10.1210/me.2015-1166
AI Summary: OriGene contributed to this study by providing plasmids encoding small hairpin RNA (shRNA) sequences targeting mouse Secretogranin III (SgIII), which were used to investigate the role of SgIII in proopiomelanocortin (POMC) trafficking.
Snippet: Plasmids encoding small hairpin RNA (shRNA) sequences targeting mouse SgIII were purchased from Origene Technologies, Inc as a set of 4
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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