Spc24 Mouse shRNA Plasmid (Locus ID 67629)
Specifications
| Product Data | |
| Locus ID | 67629 |
|---|---|
| Synonyms | 2410030K01Rik; AV109292; Spbc24 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Spc24 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 67629). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC086683, BC116238, BC116239, NM_026282, NM_001357331, NR_151672, NR_151673, NM_026282.1, NM_026282.2, NM_026282.3, NM_026282.4, NM_026282.5, BC056965, BC098472, NM_026282.6 |
| UniProt ID | Q9D083 |
| Summary | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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