Cbs Mouse shRNA Plasmid (Locus ID 12411)
Specifications
| Product Data | |
| Locus ID | 12411 |
|---|---|
| Synonyms | AI047524; AI303044; HIP4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Cbs - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 12411). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC013472, BC013480, BC026595, NM_001271353, NM_144855, NM_178224, NM_178224.1, NM_178224.2, NM_178224.3, NM_144855.1, NM_144855.2, NM_144855.3, NM_001271353.1, BC022144 |
| UniProt ID | Q91WT9 |
| Summary | Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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