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Snap25 Mouse shRNA Plasmid (Locus ID 20614)

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SKU
TL515252
Snap25 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 20614
Synonyms Bdr; GENA70; SNAP-25; sp; SUP
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Snap25 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 20614). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC018249, NM_001291056, NM_011428, NM_001355254, NM_001355255, NR_149318, NM_011428.1, NM_011428.2, NM_011428.3, NM_001291056.1
UniProt ID P60879
Summary t-SNARE involved in the molecular regulation of neurotransmitter release (PubMed:8243676, PubMed:8103915). May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF (PubMed:16672379). Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Constitutive IP3R1-mediated Ca2+ release reduces Ca2+ store content and stimulates mitochondrial metabolism in mouse GV oocytes
Wakai, Fissore
J. Cell. Sci. (2019)
AI Summary: In this study, an OriGene mouse SNAP-25 expression vector was used as the PCR template to generate a SNAP-25 mutant (SNAP25 ⊿20), contributing to investigations of Ca2+ signaling and mitochondrial metabolism in mouse GV oocytes.
Snippet: The SNAP-25 mutant (SNAP25 ⊿20 ) sequence was amplified by PCR from mouse SNAP- 25 expression vector (Origene) and subcloned into a pcDNA6/Myc-His B vector between the EcoRI and XhoI restriction sites. ATP biosensor, AT1.03 and mitochondrial Ca2+
Showing 1-1 of 1 papers.
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