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Ikbkg Mouse shRNA Plasmid (Locus ID 16151)

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SKU
TL515020
Ikbkg - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 16151
Synonyms 1110037D23Rik; AI848108; AI851264; AW124339; IKKg; NEMO
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Ikbkg - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 16151). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC021431, NM_001136067, NM_001161421, NM_001161422, NM_001161423, NM_001161424, NM_010547, NM_178590, NM_001161424.1, NM_010547.1, NM_010547.2, NM_178590.1, NM_178590.2, NM_178590.3, NM_178590.4, NM_001136067.1, NM_001136067.2, NM_001161421.1, NM_001161422.1, NM_001161423.1, BC026905
UniProt ID O88522
Summary Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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