Anp32e Mouse shRNA Plasmid (Locus ID 66471)
Specifications
| Product Data | |
| Locus ID | 66471 |
|---|---|
| Synonyms | 2810018A15Rik; AI047746; AI326868; CPD1; LANP-L; LANPL; mLANP-L |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Anp32e - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 66471). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC005690, BC080684, NM_001253757, NM_001253758, NM_023210, NM_023210.1, NM_023210.2, NM_023210.3, NM_023210.4, NM_001253758.1, NM_001253757.1 |
| UniProt ID | P97822 |
| Summary | Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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